Videos

An expert discusses how JAK inhibitors represent targeted therapy that specifically blocks the interferon gamma–driven JAK-STAT pathway responsible for autoimmune melanocyte destruction in vitiligo, offering greater efficacy and safety compared with broad immunosuppressive treatments such as corticosteroids.

An expert discusses how home administration of oncology drugs in the US faces significant logistical and reimbursement challenges—despite the safety of subcutaneous and on-body delivery systems. He highlights that regulatory barriers, practice economics, and evolving payer policies limit adoption, even as patient-reported outcomes increasingly support the value of well-tolerated, effective regimens such as those studied in MAIA.

An expert discusses how phototherapy requires 2 to 3 sessions per week in specialized light booths or home units, is particularly useful for vitiligo covering more than 10% body surface area, and can be targeted to specific areas using 308-nm lasers for smaller lesions.

1 expert in this video

An expert discusses how non-muscle invasive bladder cancer (NMIBC) creates a significant clinical and financial burden with up to 60% recurrence rates, affecting an estimated 85,000 new patients annually and requiring frequent office visits that impact quality of life for this older population.

An expert discusses the evolving role of bispecific antibodies in multiple myeloma, highlighting their off-the-shelf availability, immune-targeting mechanism, and growing potential in relapsed and frontline settings, while emphasizing the need for proactive toxicity management, personalized supportive care, and strategic integration into broader treatment plans.

An expert discusses the operational and financial complexities of integrating bispecific antibodies into multiple myeloma treatment pathways, emphasizing the need for standardized protocols, multidisciplinary training, payer-provider collaboration, and infrastructure investments to support safe, scalable, and value-based delivery of care.

An expert discusses the approval of a third bispecific antibody for relapsed/refractory multiple myeloma (R/R MM), highlighting its potential to reshape treatment pathways, intensify payer scrutiny around formulary positioning and cost-effectiveness, and drive a more competitive, real-world reassessment of the bispecific therapy class.

An expert discusses how choosing between triplet and quadruplet regimens for transplant-ineligible multiple myeloma depends on patient fitness, disease risk, and treatment tolerability. He highlights that anti-CD38 antibodies generally add minimal toxicity, triplets may offer strong outcomes for frail patients, and practical factors such as infection risk, dosing frequency, and subcutaneous vs intravenous (IV) administration also influence regimen selection.

1 expert in this video

An expert discusses how community-based gene therapy administration has broadened treatment options for patients with BCG-unresponsive NMIBC by providing easier logistics compared with complex chemotherapy regimens, ultimately expanding bladder-sparing approaches and avoiding radical cystectomy in younger, sexually active patients.

Access is the central tenet to the success of lenacapavir as a form of preexposure prophylaxis (PrEP), according to Jeremiah Johnson, the executive director of PrEP4All and Mitchell Warren, the executive director of the AIDS Vaccine and Advocacy Coalition (AVAC).

In a video interview with MHE editors, Sharon Faust, Pharm.D., MBA, senior vice president and chief pharmacy officer at Navitus Health Solutions, shared that while she originally saw herself as a scientist focused on patient care, she found that her skills in problem-solving and critical thinking were a natural fit for the business side of healthcare.