Brain imaging technique may shed light on the clinical-radiological paradox of multiple sclerosis: structural damage in the brain related to the disease does not necessarily predict clinical disability.
A Carnegie Mellon researcher and colleagues used data from smartphones and fitness trackers to build machine learning models to predict depression, fatigue, poor sleep quality and worsening multiple sclerosis symptoms.
The link between higher multiple sclerosis rates and distance from the equator has commonly been explained by vitamin D levels. A new analysis from Johns Hopkins researchers suggests the association may also be linked to healthcare spending and the resources needed to diagnose disease.
Research conducted in Canada suggests that people with multiple sclerosis would benefit from being seen by nurse practitioners. However, secondary outcomes in the study did not improve among patients with access to nurse practitioner-led care.
Research shows that patients with multiple sclerosis who have been treated with drugs that target CD20 B cells drugs, such as Ocrevus and Rituxan, tend to have a weak antibody response. But cellular immunity and T cells are activated. The results suggest a need for vaccines that boost T cells.