News|Videos|July 8, 2026

The difference between a monoclonal antibody and a vaccine may surprise you

Author(s)Logan Lutton

Marc Elia of Invyvid explains the difference between vaccines and monoclonal antibodies.

Many people overlook the fundamental difference between vaccines and monoclonal antibodies, but the distinction matters, according to Marc Elia, Chairman of the Board of Invivyd, which is a biopharmaceutical company. In this clip, Elia explains that while a vaccine acts as an educator for the immune system, potentially triggering inflammation and discomfort in the process, monoclonal antibodies take a different approach. By providing the body with the specific antibodies it needs, this method effectively bypasses the challenging learning phase of vaccination entirely

Invivyd is developing an investigational COVID-19 monoclonal antibody called VYD2311.

The company recently completed enrollment in its phase 3 LIBERTY trial, which will test the safety and tolerability of VYD2311 compared with an mRNA COVID‑19 vaccine.


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