Expert Interviews

Vertically integrated health plans are starting to fall by the wayside due to their limited flexibility, while modular health plans are gaining traction, according to Scott Rossignol, senior director of Drug Value Strategy at Abarca Health.

Employers are demanding more transparency and partnership from pharmacy benefit managers (PBMs), according to Karen van Caulil, Ph.D., president and CEO of the Florida Alliance for Healthcare Value, who spoke with MHE ahead of her remarks at the Pharmacy Benefit Management Institute’s annual meeting in Orlando.

An expert discusses how data from the pivotal phase 3 trials of topical ruxolitinib showed 30% of patients achieved 75% improvement in facial vitiligo at 24 weeks, with real-world experience confirming these results and demonstrating that longer treatment periods and combination with phototherapy can further enhance repigmentation outcomes

An expert discusses how JAK inhibitors represent targeted therapy that specifically blocks the interferon gamma–driven JAK-STAT pathway responsible for autoimmune melanocyte destruction in vitiligo, offering greater efficacy and safety compared with broad immunosuppressive treatments such as corticosteroids.

An expert discusses how home administration of oncology drugs in the US faces significant logistical and reimbursement challenges—despite the safety of subcutaneous and on-body delivery systems. He highlights that regulatory barriers, practice economics, and evolving payer policies limit adoption, even as patient-reported outcomes increasingly support the value of well-tolerated, effective regimens such as those studied in MAIA.

An expert discusses how phototherapy requires 2 to 3 sessions per week in specialized light booths or home units, is particularly useful for vitiligo covering more than 10% body surface area, and can be targeted to specific areas using 308-nm lasers for smaller lesions.

1 expert in this video

An expert discusses how non-muscle invasive bladder cancer (NMIBC) creates a significant clinical and financial burden with up to 60% recurrence rates, affecting an estimated 85,000 new patients annually and requiring frequent office visits that impact quality of life for this older population.