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2025 Fall Clinical Dermatology|

Between the Lines: Diving Deeper Into the EMERALD Trial

Opinion|Videos|April 4, 2025

Evaluating Five-Year Efficacy Outcomes in EMPOWER-LUNG 1

Author(s)Eric K. Singhi, M.D., Ben Creelan, M.D.

Panelists discuss how the five-year prognosis for advanced non-small cell lung cancer (NSCLC) has improved with PD-1 inhibitors, showing promising overall survival (OS) and progression-free survival (PFS). Cemiplimab’s outcomes align well with other PD-1/PD-L1 inhibitors, influencing clinical decisions for its use as a first-line treatment.

Episodes in this series

2 experts in this video

EP. 1 Setting the Stage: Immunotherapy’s Impact and EMPOWER-Lung 1 Study Design

2 experts in this video

EP. 2 Optimizing First-Line and Sequential Therapy in Advanced NSCLC

2 experts in this video

EP. 3 EMPOWER-Lung 1: Baseline Characteristics and Modern Treatment Considerations in NSCLC

2 experts in this video

EP. 4 Evaluating Five-Year Efficacy Outcomes in EMPOWER-LUNG 1

2 experts in this video

EP. 5 Subgroup Analyses of EMPOWER-LUNG 1

2 experts in this video

EP. 6 Managing Safety and Quality of Life With Cemiplimab in Advanced NSCLC

2 experts in this video

EP. 7 The Role of Continuing Cemiplimab in Second-Line Therapy After Progression

2 experts in this video

EP. 8 Closing Insights: The Future of Cemiplimab in NSCLC and Beyond

EP. 9 Evaluating Five-year Efficacy Outcomes in the EMPOWER-Lung 1 Study | Written Recap

EP. 9 Evaluating Five-year Efficacy Outcomes in the EMPOWER-Lung 1 Study | Written Recap

Video content above is prompted by the following:

What is the current five-year prognosis for advanced NSCLC in terms of overall survival and progression-free survival?
How do the reported OS and PFS outcomes compare with other PD-1/PD-L1 inhibitors in the setting of advanced NSCLC?
How does this new five-year data impact clinical decision-making for cemiplimab as a first-line treatment for patients with advanced NSCLC?

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