News

The Infectious Diseases Society of America updates flu and RSV vaccine guidelines, emphasizing safety for immunocompromised patients during respiratory virus season.

Medicaid expansion increased overall PrEP access in the U.S., but significant racial, gender and structural disparities persist, limiting equitable HIV prevention despite rising national uptake.

Redemplo has been approved to treat adults with familial chylomicronemia syndrome. The therapy will be available by the end of the year and will have an annual wholesale acquisition cost of $60,000.

A new study suggests epigenetic changes at Type 1 diabetes susceptibility genes may explain the risk profile of children born of parents with the disease.

The findings in a new study published in Health Affairs suggest that Semglee’s interchangeability status may have partially increased adoption by supporting improved formulary coverage.

In this latest episode of his “Conversations With Perry and Friends” podcast, Perry Cohen, Pharm.D., a member of the Managed Healthcare Executive editorial advisory board, spoke with C. Daniels Mullins, Ph.D., a professor of practice, sciences, and health outcomes research at the University of Maryland School of Pharmacy in Baltimore and a pioneer in incorporating the patient point of view into research and healthcare.

Sandoz’s Tyruko (natalizumab), the only FDA approved natalizumab biosimilar for adults with relapsing multiple sclerosis and Crohn’s disease, is now available by prescription in the United States under a restricted-distribution program because of the drug’s risk of progressive multifocal leukoencephalopathy.

In addition, Elevidys’s indication for non-patients has been removed, and the gene is now indicated only to treat ambulatory patients four years of age and older with Duchenne muscular dystrophy.

Healthcare is treated as an investment good in Spain in contrast to the American framing, which treats healthcare as a consumer good.

High levels of integrin beta-6 (IB6) in metastatic non-small cell lung cancer suggest that it could be a target for treatment.

The investigational lenacapavir-bictegravir tablet has the potential to reduce the pill burden of HIV treatment, according to a recent news release.

The FDA has approved Poherdy as the first interchangeable biosimilar to Perjeta, expanding treatment options for adults with HER2-positive breast cancer across both early-stage and metastatic settings.

mRNA COVID-19 vaccines enhance immune responses, improving cancer treatment outcomes with immune checkpoint inhibitors and offering hope for hard-to-treat tumors.

New research highlights DR-70 as a promising noninvasive biomarker for diagnosing and staging bladder cancer, potentially improving early detection strategies.

In this interview, Lasara Firefox Allen, MSW, shares insights on gender-affirming menopause care, the unique needs of gender-diverse individuals and the importance of educating healthcare providers to offer inclusive support.

Results from two studies show that fenebrutinib significantly reduced relapses and slowed disease progression when compared with currently available treatments.

A study reveals circulating tumor cells (CTCs) as potential biomarkers for predicting aggressive DCIS, aiming to reduce overtreatment and improve patient outcomes.

Veterans in the healthcare workforce are promoted more often and stay longer than non-veteran peers, highlighting their valuable leadership skills amid growing national healthcare staffing shortages.

The immunosuppressive drugs used in severe COVID-19 cases might leave patients vulnerable to shingles.

After reviewing new data that proves hormone replacement therapy does not increase a woman’s risk of receiving a breast cancer diagnosis, the FDA has removed the black box label.

AI transforms healthcare by enhancing disease detection, patient care and hospital efficiency but requires careful implementation to ensure equity and effectiveness. Managed Healthcare Executive sought for common themes in where AI currently stands in healthcare by analyzing our past coverage in the past.

Here’s what you missed this week on Managed Healthcare Executive.

An off-target interaction with nuclear receptor PPARγ may trigger a sequence of events that results in lung injury.

Milliman’s Jennifer Cruz says plans are losing rebates because of steep price discounts negotiated under the Inflation Reduction Act. but that they need to be sure that renegotiation of rebate guarantees doesn’t get too broad.

Pharmacy benefit managers are approaching health plans with value-based contracts that consider lower costs on the medical benefit of the insurance, says Jennifer Cruz of Milliman.