Acute Pain

A new study found a specific brain and spinal cord circuit that appears to cause chronic pain after injury and could one day be targeted to treat pain without affecting the body's normal protective pain responses.

One year after FDA approval, Journavx (suzetrigine) offers a promising non-opioid option for acute pain, but experts have concerns about long-term safety, opioid-sparing effects and real-world use.

USF Health researchers have discovered how opioid receptors work in reverse, which could allow for medications to boost pain relief without causing dangerous side effects.

Chronic back pain amplifies sound unpleasantness; fMRI links it to sensory circuits, and pain reprocessing therapy may help normalize responses.

In an overview of systematic reviews, researchers found that opioid analgesics have a role in the management of some acute pain conditions, such as postsurgical dental pain, with moderate evidence.

Phase 4 acute pain study shows Journavx helps more than 90% of plastic surgery patients achieve opioid-free recovery with strong ratings and mild side effects.

The combination of acetaminophen and morphine provides slightly better early pain relief than morphine alone in emergency departments, particularly for patients with nontraumatic, nerve-related pain.

A systematic review and meta-analysis found some supporting evidence for transdermal anti-inflammatory patches, but the results might be described as, well, patchy.

For people with pain hyperacusis, everyday sounds trigger pain. The condition can lead to social isolation and worse. Treatment options are limited.

Positive results reported for pain from knee osteoarthritis among those who have obesity.

The biggest advantage of suzetrigine would be that it helps patients avoid the use of opioids for acute pain. The FDA’s goal date for suzetrigine is Jan. 30, 2025.

Prescription of Neurontin (gabapentin) and other gabapentinoids has increased partly because they are viewed as a safer alternative to opioids.

Laser therapies may help with pain after a root canal, but a review of published studies shows their effectiveness can vary significantly. Further research is needed to identify the optimal approach.

The new J-code will become effective in January and will provide reimbursement when Exparel is used in the office setting and for office-based surgeries.

Survey finds that people with chronic pain were more supportive of the policies that would expand access to medical cannabis.

A review of skeletal muscle relaxants shows that they don't work for pain from osteoarthritis, neuropathic pain and other conditions. Some see an opportunity for more tailored therapeutic strategies, improving patient outcomes.

The future of pain medicine is characterized by treatments and technologies — including virtual reality, AI, wearable tech and psychedelics — that promise to significantly enhance patient care.

A systemic review of corticosteroid studies finds that their anti-inflammatory effects can be beneficial in addressing peripheral injuries and as a adjuvant for treating the associated pain.

The two clinical trials will enroll patients recovering from surgical procedures.

The interplay between chronic pain and HIV can complicate treatment regimens, negatively impact functional abilities, and diminish overall quality of life for affected individuals.

The management of pain in older adults with cancer remains a significant public health concern and an unmet medical need, particularly in rural areas. This demographic often encounters specific challenges, such as limited access to healthcare services, hesitancy to talk about pain, and misunderstandings about pain management.

Shoulder pain can originate from various sources, such as osteoarthritis, post-operative discomfort, musculoskeletal injuries like a torn labrum, neuralgia and paralytic shoulder injury. Recent research has shown that PNS can effectively manage chronic and acute pain.

Suzetrigine, a new type of pain medication, has a Prescription Drug User Fee Act target action date of Jan. 30, 2025, for patients with acute pain.

Like fish oils, krill oil also contains omega-3 fatty acids and has a comparably better bioavailability than fish oil. Additionally, krill oil contains a potent antioxidant known as astaxanthin, which may reduce inflammation resulting from free radicals.