Collagen Stimulator Filler Trend Fixes "Overfilled" Social Media Look | 2025 Fall Clinical Derm

In aesthetic dermatology, collegen stimulators are in and hyaluronic acid fillers are out, according to Mark S. Nestor, M.D., Ph.D., a dermatologic surgeon practicing in Aventura, Florida.

This switch is due to two reasons, social media trends and the fact that people are looking for a healthier, more natural look.

"It comes from social media and this whole thing of the overfilling syndrome that that was there for a long time, that people were getting too much. They were looking bizarre. A lot of stars, they looked weird,” Nestor said in a recent video interview with Managed Healthcare Executive.

Collegen stimulators are also a healthier, longer-lasting option.

"What has increased significantly is the use of collagen stimulators like PLLA [poly-L-lactic acid] specifically, where it's improving the quality of the skin as well as volumizing as well," Nestor said.