Autoimmune Diseases

Manipulating T cells to target cancer cells has worked to treat some cancers. Researchers are investigating whether the same approach might be used to curb the dysregulated immune response that underlies autoimmune disease.

New analyses shed light on decreased hearing in people with Graves’ disease and thyroid eye disease.

Rates of Graves’ disease, celiac disease, and Sjögren’s syndrome doubled in the United Kingdom between 2000 and 2019.

Low-to-moderate doses of prednisone appear to lessen rates of nausea and other side effects in patients taking methotrexate, a new study found.

Stimulating PD-1 is a novel approach to treating rheumatoid arthritis, but the strategy could be a fit for other autoimmune diseases.

Kevzara is the first biologic to treat patients with polymyalgia rheumatica (PMR). It is also approved to treat rheumatoid arthritis.

The real impact may not likely be seen until after July when additional biosimilars referencing Humira are launched.

A decision is anticipated in early January about which of the now eight Humira biosimilars will be included.

This is the eighth biosimilar to reference the blockbuster rheumatoid arthritis drug Humira that will launch in 2023.

The FDA approval in active ankylosing spondylitis is the fifth indication for Rinvoq in chronic immune-mediated diseases. It joins Xeljanz, which was the first approved JAK inhibitor for this condition in December 2021.

Merck will withdraw Keytruda's advanced gastric indication after an FDA panel vote, a drug with supply problems gets a new indication, NDAs for an HIV therapy, and other news.

Telehealth during the COVID-19 pandemic has been especially important to patients with rare disorders, many of which are autoimmune diseases, according to a recent report from the National Organization for Rare Disorders.

New data presented recently at the American College of Rheumatology meeting add to the evidence in support of anifrolumab, which could address unmet need in lupus.

Rather than stopping hydroxychloroquine altogether, doses could be reduced and patients monitored if there are signs of retinopathy, say the authors of a commentary in the American Journal of Ophthalmology.

Central obesity may be especially unhealthy for people with the inflammatory condition that affects the spine.

Research documents that the disease affects men and women differently.

An immunotherapy combination gets a third thoracic indication; another potential indication for an SGLT2 inhibitor.

Fatigue causes a complex array of problems for people with autoimmune disease.

Study of the quality of life of psoriatic arthritis patients reveals the added burden of skin symptoms.

FDA actions for the week ending August 21, 2020, include a hearing set for a drug that could limit weight gain often associated with treatment for serious mental illness.

Celiac disease was linked with a greater likelihood to be diagnosed with a mood disorder, ADHD, or an eating disorder.

A recent study found 64% of patients with psoriatic arthritis who had tried at least one biologic stayed with Cosentyx for the entire study period.

Preliminary findings by Case Western researchers point to kallikrein-related peptidase 6 as possible culprit in the development of psoriatic arthritis.

Potential agents to battle inflammation and other processes move through development pipeline.

A look at recent developments in treatment and the cost implications of various autoimmune diseases.

The food people eat and the toxins they are exposed to on a daily basis are two of the biggest contributors to the likelihood of developing an autoimmune disease, according to many health experts.

Protein produced by common gut bacteria may trigger the onset of autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and ulcerative colitis.

Although it’s still unknown what the mechanisms are that contribute to MS-related fatigue, certain dietary approaches can help treat it.

A Yale University study has revealing findings about how diet impacts patients with lupus.

A new Chinese study highlights a potential cell therapy strategy for autoimmune diseases in a clinic setting.