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Results point to the benefit of adding Darzalex (daratumumab) to Velcade-Revlimid-dexamethasone triplet therpay, although serious side effects seem be slightly more common when Darzalex is added.

Trial results revealed that tumors shrank in 40% of patients who received the 10-mg dose of tarlatamab and in about 32% of those who received the 100-mg dose.

Results reported in JAMA Psychiatry today show no difference in effectivenes between at-home cranial stimulation and sham treatment.

A subset of natural killer cells may be a potential target for the development of agents protective against MS.

Inflammatory bowel disease (IBD) clinical trials often involve participants getting numerous endoscopies. Cutting back on the number of endoscopies and using noninvasive tests instead was one of the ideas discussed for how to improve clinical trial design.

We asked 16 industry professionals what their predictions are for health care in 2024.

Brent Dover is the CEO of Carta Healthcare. He predicts that AI use will reach new heights.

Matt Hollingsworth is the Chief Innovation Officer and Co-Founder of Carta Healthcare. He said there will be a growing need for technology in 2024.

Greg Baker is the CEO of AffirmedRx. He predicts that "transparent PBMs will gain traction" in 2024.

Fran Gregory, Pharm.D., MBA is the Vice President of Emerging Therapies at Cardinal Health. She thinks 2024 will be an exciting year for cell and gene therapy.

Melynda Barnes, M.D. is the Chief Medical Officer at Ro. She believes "more people will gain access to GLP-1 inhibitors" in 2024.

Michael Meucci is the CEO of Arcadia. He thinks that EHRs will get an AI makeover.

Maulik P. Purohit, M.D., M.P.H., is the Chief Health Information Officer at the Lehigh Valley Health Network. He believes that "AI will enhance the patient experience" in 2024.

Joerg Schwarz, M.S., is the Senior Director of Healthcare Interoperability at Infor. He believes providers will harness the power of generative AI in 2024.

Brianna Zink, M.S.N, is the Senior Director of Health Care Product Strategy at Infor. She says staff ratios will become a burden in 2024.

This year's top multimedia content includes a video interview with Jennifer Roggenbuck, MS, LGC, of Ohio State University, who addresses the patient journey of ALS.

Laura Kline, MBA, CPCU is the Senior Vice President of Business Development at The Doctors Company. She predicts "APCs will be critical to access care."

Casberg is Vice President of Clinical Pharmacy at IPD Analytics LLC and a member of the Managed Healthcare Executive editorial advisory board. He predicts that "payers will tighten" in 2024.

This year's top HIV articles include one sharing data from a group of researchers from University of Pittsburgh who looked to see if T cell activation is sufficient to drive SIV disease progression.

Kelsay is the President and CEO of the Business Group on Health. She predicts that in 2024, employers will "sound the drug price alarm."

Robert E. White Jr. is the President of The Doctors Company. He believes "social inflation will affect malpractice insurers."

This year's top oncology news included a study that suggested low-fat meals could affect blood concentration levels, and high blood concentration has been associated with a better response to the drug, Alecensa.

Weight-loss medications were very much in the news this year, and the pages and website of Managed Healthcare Executive were no exception. Articles on off-label use of the GLP-1s such as Ozempic (semaglutide) and the FDA approval of Zepbound (tirzepatide) garnered the most page views.

Articles about Humira biosimilars, over-the-counter hearing aids and specialty drugs were among those about healthcare and drug costs that had the most pageviews on the MHE website in 2023.

News about state bans on accumulators, Pfizer’s announcements about vaccines and cardiovascular deaths increasing because of climate change were the most viewed news items on the Managed Healthcare Executive website this year.

Men with severe or moderately severe hemophilia B continue to display low bleeding rates and very little use of replacement therapies for at least three years following a single dose of the approved gene therapy hemgenix.