June 11th 2025
Cutaneous squamous cell carcinoma (cSCC) is the second most common form of skin cancer. While most cases are treatable, a small number can become serious and spread, leading to worse outcomes.
Alefacept: A T-cell-specific immunosuppressant to treat moderate to severe plaque psoriasis (PDF)
July 1st 2002Alefacept (Amevive) is the first immunosuppressive agent directed specifically at inhibiting the activation of, and possibly killing, T cells, which are involved in the cascade of events leading to psoriatic plaque formation and inflammation. In May, an FDA advisory committee recommended alefacept for approval as a first-line therapy against moderate to severe plaque psoriasis. The authors of this Focus article review the clinical characteristics of alefacept as well as make comparisons with other systemic drugs currently used to treat chronic psoriasis and the likely biologic competitors etanercept and infliximab.
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Atopic Dermatitis: Disease Overview and the Development of Topical Immunomodulators (PDF)
May 1st 2002Atopic dermatitis is a chronic, recurrent skin disease characterized by intense pruritis (itching) and inflammation. This supplement which was produced through an unrestricted educational grant from Fujisawa Healthcare, Inc. provides you with an overview of the disease and the development of Topic Immunomodulators. The views and opinions expressed in this supplement do not necessarily reflect the views of Formulary.
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Biologics new and old may offer long-term management option for psoriasis
April 1st 2002An array of both existing and investigational biologic agents are showing efficacy in clearing psoriasis and may prove useful for long-term psoriasis management. So suggests a collection of studies presented at the 60th annual meeting of the American Academy of Dermatology, held recently in New Orleans.
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