New real-world data suggest that physicians are cautious about prescribing the prostacyclin-receptor agonist Uptravi (selexipag) to pulmonary arterial hypertension (PAH) patients with mental health conditions when evidence suggests that it is best to take a proactive approach to treating PAH.
The results come from a phase IIa safety and tolerability study. The drug’s developers say they are working with regulatory authorities in hopes of launching a pivotal trial.
Artificial intelligence is quickly becoming a valuable tool in the U.S. healthcare industry. Experts say a thoughtful approach can head off ethical problems and optimize efficiency.
Preclinical data had suggested reducing serotonin might improve symptoms of pulmonary arterial hypertension, but new phase 2b data suggest the opposite.
New anecdotal evidence suggests some chemoimmunotherapy treatments may improve pulmonary arterial hypertension symptoms, but the overall evidence remains murky.
Investigators say more research is warranted to optimize management of patients with pulmonary arterial hypertension (PAH) who become pregnant.
Telehealth has become a permanent part of U.S. healthcare delivery, and states are taking steps to regulate it
Individualized digital twins offer the prospect of better predicting individual patients’ disease progression and response to therapy.
The approval comes five months after the FDA approved Winrevair.
Recent research affirms the apparent utility of deep learning to build early detection models for pulmonary arterial hypertension.
Evidence suggests resistin is high in serum samples of people with severe pulmonary arterial hypertension; reducing it may reduce disease severity.
The committee in charge of reviewing medications for the European Medicines Agency has issued a positive recommendation for the single-tablet combination therapy of macitentan and tadalafil.
Artificial intelligence gains foothold in the emergency room as a note-taking aid.
Patients with pulmonary arterial hypertension and cardiopulmonary comorbidities are typically started on monotherapy, but new data suggest some patients would do well with initial combination therapy.
A European committee has recommended sotatercept (Winrevair) be approved for certain patients with pulmonary arterial hypertension. A final decision is expected sometime this quarter.
By creating digital models based on individual patients, clinicians might one day be better able to personalize care.
A new report finds commercial insurers are adding more restrictions on therapies for pulmonary arterial hypertension.
Investigators are considering how best to interpret the results of potential new therapies.
A new report aims to create consistency out of a number of observations about associations between echocardiographic values by analyzing them in the context of real-world patient outcomes.
On the heels of Winrevair's approval, Gossamer Bio and the Chiesi Group struck a deal to develop seralutinib.
Preliminary data suggest people with Group 1 pulmonary hypertension had improved outcomes if they had ever received hormone replacement therapy.
Research shows health-related quality of life is impacted in major ways by pulmonary arterial hypertension, but a solution to the problem—and the disease itself—has proven elusive.
Healthcare organizations generate and store vast amounts of data but they often have to choose between speed and structure. Data "lakehouses" may be the answer.
The Boomers (1946–1964): Active but aging
The imperative to upgrade healthcare technology infrastructure is clear, but the returns from such investment are anything but.
Hospitals and healthcare software developers are adjusting to a world in which blocking healthcare data will come with potentially stiff penalties under rules proposed by the Office of the National Coordinator for Health Information Technology (ONC).
xCures says artificial intelligence and machine learning can help make sense of disparate medical records.
Mahana’s company’s irritable bowel syndrome digital therapy was the first to digital therapy to gain clearance from the FDA.
Interoperability has been an aspiration in the healthcare IT world for many years. The finalization of new rules means they finally have a chance to prove its merits.
Improving patient monitoring through care-at-home services could help reduce maternal mortality, they say.
