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Opinion|Videos|September 30, 2025

Understanding the Clinical Needs and Real-World Data in BCG-Unresponsive NMIBC

Author(s)Max Kates, MD

An expert discusses how BCG-unresponsive NMIBC patients have heterogeneous clinical needs requiring individualized treatment strategies, while P&T committees evaluate new therapies by assessing unmet needs and comparing real-world evidence across single-arm trials.

Episodes in this series

1 expert in this video

EP. 1 Evolving Guidelines: Impact of Gene Therapy and BCG Failure Redefinitions on High-Risk NMIBC Patient Management

1 expert in this video

EP. 2 Applying Evidence Standards to Guide Gene Therapy Use in BCG-Unresponsive NMIBC

1 expert in this video

EP. 3 Impact of Real-World Treatment Experience on Gene Therapy Uptake in NMIBC

1 expert in this video

EP. 4 Navigating Challenges and Impact on Workflow with New NMIBC Therapies in Practice

1 expert in this video

EP. 5 Effective Strategies for Clinics Preparing to Implement Gene Therapy Into NMIBC Treatment Workflows

1 expert in this video

EP. 6 Reducing Clinical Resource Burden: Impact of Less Frequent NMIBC Therapy Administration

1 expert in this video

EP. 7 How Community-Based Gene Therapy Is Changing Treatment and Improving Quality of Life for Patients With BCG-Unresponsive NMIBC

1 expert in this video

EP. 8 Understanding NMIBC and Its Risk Factors

1 expert in this video

EP. 9 Navigating Treatment Burden in NMIBC

1 expert in this video

EP. 10 When BCG Falls Short: What’s Next for NMIBC Patients?

1 expert in this video

EP. 11 A New Era: The Rise of Gene Therapy in NMIBC

1 expert in this video

EP. 12 Where Do We Go From Here? Overcoming Barriers in NMIBC Care

EP. 13 Bridging the Gap Between Clinical Trial Evidence and Real-World Practice in NMIBC

1 expert in this video

EP. 14 Coverage Criteria and Clinical Evidence Used to Shape Health Plan Formulary Decisions in BCG-Unresponsive NMIBC

1 expert in this video

EP. 15 Prioritizing Safety and Efficacy: Role of Guidelines in NMIBC Formulary Decisions

1 expert in this video

EP. 16 Evaluating Cost-Effectiveness of NMIBC Therapies From a Health Plan Perspective

1 expert in this video

EP. 17 Leveraging Real-World Evidence in NMIBC Therapy Evaluations

1 expert in this video

EP. 18 Administration Matters: How Dosing Frequency and Toxicity Shape NMIBC Coverage Decisions

1 expert in this video

EP. 19 Access Barriers in NMIBC: Financial, Operational and Systemic Challenges With Emerging Therapies

1 expert is featured in this series.

EP. 20 Understanding the Clinical Needs and Real-World Data in BCG-Unresponsive NMIBC

1 expert is featured in this series.

EP. 21 Evaluating Emerging NMIBC Therapies Through Long-Term Data and Real-World Outcomes

1 expert is featured in this series.

EP. 22 Balancing Treatment Burden, Access Barriers, and Future Research of BCG-Unresponsive NMIBC

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