News|Videos|July 18, 2025

Price, Scalability of Lenacapavir as PrEP Curbs Excitement, Expert Says

Author(s)Logan Lutton

Although the FDA approval of lenacapavir as a twice-yearly form of preexposure prophylaxis (PrEP) is “momentous,” cost and access curb excitement, according to Jeremiah Johnson, executive director of PrEP4All.

To reap the full benefit of lenacapavir as a form of preexposure prophylaxis (PrEP), it must be accessible, according to Jeremiah Johnson, executive director of PrEP4All.

Generic lenacapavir could cost as low as $35-$46 per person per year, falling to as low as $25 per person per year, depending on demand, a recent study published in The Lancet reads. The list price in the United States is currently $28,218 per person per year.

“At the end of the day, the best PrEP for somebody is going to be the one that they can actually access,” Johnson said during a recent interview with Managed Healthcare Executive. “I don't want people to throw the baby out with the bathwater when we have a daily oral generic of Truvada that is less than $1 a day that may be more feasibly scaled, particularly for some of the communities that are going to fall into the cracks of the American healthcare system.”


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