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Secondary Progressive Multiple Sclerosis: Patient Impact and Coverage Implications for New Therapies

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Laura is the vice president of content of Managed Healthcare Executive

 (MHE) and all its brands, including Formulary Watch

. She has been working on MHE since 2019 and has been with MHE's parent company, MJH Life Sciences

, since 2011. She has an MA in business and economic reporting from New York University.

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Secondary Progressive Multiple Sclerosis: Patient Impact and Coverage Implications for New Therapies EP8

Challenges Regarding Coverage for New SPMS Therapies

Evolving Treatment Strategies and Coverage Implications

The Clinical and Economic Burden of SPMS

Fred Lublin, MD, says it's possible health professionals can develop some biomarkers and find some differences in advanced MRI metrics in finding Secondary Progressive Multiple Sclerosis.



Determining SPMS as Biological Instead of Classification

Thomas P. Leist, MD, PhD, discusses secondary progressive MS, more specifically how very early control of the disease gives the patient the best chance for long term stability and gives the patient, the best chance of not entering the secondary state.


Tackling Secondary Progressive Multiple Sclerosis Early on Benefits Patients in a Number of Ways

Thomas P. Leist, MD, PhD, says doctors working with patients diagnosed with SPMS don't necessarily have prognostic biomarkers to detect SPMS. The best prognostic biomarkers they have currently are MRI and potentially neurofilament light. He adds their techniques need to improve in order to harness the full benefit of potentially individualizing care to the most optimal fashion in a given patient.

Biomarkers Used to Detect Secondary Progressive MS Needs Improvement for the Care of Patients

Defining active SPMS

Thomas P. Leist, MD, PhD, explains that there is no such thing as "one size fits all" for patients with SPMS. Patients can be impacted differently based on how they present themselves and how they behave.


How Patients Present SPMS, How to Act on it

Fred Lublin, MD, says a new labeling indication of Secondary Progressive Multiple Sclerosis broadens whom you can treat. He adds this will be very helpful to patients because it will treat groups that are progressing slowly without agents of activity.


A Labeling Indication of SPMS Can Treat More Patients

Thomas P. Leist, MD, PhD, says one of the things secondary progressive multiple sclerosis professionals struggle with is making the most effective treatment available to patients, very early on, most likely due to financial reasons.

The Struggle of Making an Effective SPMS Treatment Early on

Unmet Needs for All and Most Vulnerable Secondary Progressive MS Patients

Population Health Perspectives is a recurring content series published on MHE and Formulary Watch through print, digital and video avenues. The series focuses on updates around new real-world evidence/data and trends that stand to impact treatment guidelines, access decisions, and patient experience.