Breyzani Approved For CLL/SLL and FDA Advisory Committee Votes in Favor of Abecma for MM
March 21st 2024Last week, BMS announced that the FDA Oncologic Drugs Advisory Committee (ODAC) has voted in favor of BMS’s and 2seventy bio's Abecma (idecabtagene vicleucel) for patients with relapsed or refractory multiple myeloma in earlier lines of therapy.
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The trial evaluated Adcetris in combination with Revlimid and Rituxan compared to Revlimid and Rituxan plus placebo in adult patients with relapsed/refractory DLBCL who have received two or more prior lines of therapy and are ineligible for stem cell transplant or CAR-T therapy.
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The other, smaller (cell) lung cancer
March 18th 2024Small cell lung cancer is a less common form of lung cancer and very aggressive. Researchers and drug developers are looking for new treatments, especially for patients whose cancers have stopped responding to first- and second-line treatments. Tarlatamab, a bispecific T-cell engager, looks promising as a third-line treatment.
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Study Suggests Role of Immunogenetic Associations in Lung Cancer Risk
March 7th 2024In the U.S., nearly 200,000 new cases of lung cancer were reported in 2020, with over 100,000 deaths. While the number of lung cancer deaths has generally decreased over the past 20 years, lung cancer remains the leading cause of cancer deaths in the US and is the third most common type of cancer.
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Promising Results for Investigational mRNA Vaccine Against CMV
February 16th 2024A study found that the mRNA-1647 vaccine candidate developed by Moderna elicited strong immune responses. The mRNA vaccine is now in phase 3 clinical trials to determine its effectiveness in protecting against CMV.
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New Study Suggests Effective Management Strategies for High Blood Pressure with Imbruvica
February 13th 2024Imbruvica is an oral medication prescribed to treat certain B-cell malignancies, including chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) and Waldenstrom macroglobulinemia.
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New Study Shows Racial Disparities in Treatment and Survival Among Seniors with Multiple Myeloma
February 7th 2024The development of new and improved therapeutic agents has improved the treatment outcomes for MM over the past few decades. It remains unclear whether these racial disparities have persisted in the era of novel agents.
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Study: Long-Term Smoking Cessation Linked to Lower Cancer Risk, Even with Relapses
February 6th 2024It is well-known that smoking is linked to a higher risk of cancer, and those who smoke can lower their risk by quitting. However, it remains unclear exactly how many years of continued smoking cessation are needed to see a substantial risk reduction.
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Liquid Biopsy May Guide Treatment and Improve Outcomes in Lung Cancer, New Study Shows
January 8th 2024While tissue biopsy is currently recommended as the gold standard for determining mutations in non-small cell lung cancer, its success is not guaranteed, prompting the consideration of the liquid biopsy method as a viable alternative.
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