CDC Approves New Recommendations for RSV Vaccine in Adults
July 12th 2024According to the new recommendations, ACIP recommends that adults ages 75 years and older receive a single dose of RSV vaccine. It is a single-dose-per lifetime recommendation, so those who have already received a dose of RSV vaccine in the past are not recommended to receive an additional dose.
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Digital Tools Utilizing Patient Health Records Improve Lung Cancer Screening Rates
July 4th 2024Researchers from the University of Utah in Salt Lake City have developed a more comprehensive, multifaceted digital tool for lung cancer screening that integrates into EHR as well as patient portals. Their paper was published in JAMA Network Open in June 2024.
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Meta-Analysis Explores RSV Incidence and Outcomes in Pregnant Women
June 18th 2024In most healthy adults, RSV is mild or asymptomatic, but it can cause severe illness or hospitalization in babies, young children, older adults and pregnant women, in particular, with potential complications including pneumonia, sepsis and preeclampsia.
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Study Shows Notable Age-Specific Risk Factors for Severe RSV Infection in Children
June 14th 2024A recent study of children with RSV conducted by St. Jude faculty member M. Asunción Mejías, M.D., Ph.D., and colleagues emphasizes that the risk of RSV extends past infancy. The study also highlights age-specific factors associated with severe disease.
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The Role of Pharmacogenomics in Reducing Racial Disparities in Pediatric AML Treatment Outcomes
May 20th 2024A new study in JAMA Network Open suggests that disparities in outcomes between Black and White children with acute myeloid leukemia may be due to differences in pharmacogenomics, which is how genes affect drug responses.
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Two Opdivo Updates from Bristol Myers Squibb
May 14th 2024First approved by the U.S. Food and Drug Administration (FDA) in 2014, Opdivo has multiple indications across various types of cancer, including NSCLC, melanoma, renal cell carcinoma, Hodgkin lymphoma, squamous cell carcinoma of the head and neck, and urothelial carcinoma.
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Breyzani Approved For CLL/SLL and FDA Advisory Committee Votes in Favor of Abecma for MM
March 21st 2024Last week, BMS announced that the FDA Oncologic Drugs Advisory Committee (ODAC) has voted in favor of BMS’s and 2seventy bio's Abecma (idecabtagene vicleucel) for patients with relapsed or refractory multiple myeloma in earlier lines of therapy.
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The trial evaluated Adcetris in combination with Revlimid and Rituxan compared to Revlimid and Rituxan plus placebo in adult patients with relapsed/refractory DLBCL who have received two or more prior lines of therapy and are ineligible for stem cell transplant or CAR-T therapy.
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The other, smaller (cell) lung cancer
March 18th 2024Small cell lung cancer is a less common form of lung cancer and very aggressive. Researchers and drug developers are looking for new treatments, especially for patients whose cancers have stopped responding to first- and second-line treatments. Tarlatamab, a bispecific T-cell engager, looks promising as a third-line treatment.
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Study Suggests Role of Immunogenetic Associations in Lung Cancer Risk
March 7th 2024In the U.S., nearly 200,000 new cases of lung cancer were reported in 2020, with over 100,000 deaths. While the number of lung cancer deaths has generally decreased over the past 20 years, lung cancer remains the leading cause of cancer deaths in the US and is the third most common type of cancer.
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