Provention Bio Chooses Amber as Specialty Pharmacy for Tzield

Amber Specialty Pharmacy will be dispensing Provention Bio’s Tzield (teplizumab) to delay the onset of stage 3 type 1 diabetes. It is indicated for adults and pediatric patients 8 years and older who currently have stage 2 type 1 diabetes. Tzield is anti-CD3-directed antibody, and binds to CD3, a cell surface antigen present on T lymphocytes. Tzield is administered by intravenous infusion once daily for 14 consecutive days.

The specialty pharmacy, Hy-Vee subsidiary, has 19 locations with ambulatory and home infusion capabilities.

“Living with or caring for a child with type 1 diabetes requires constant daily management,” Kristin Williams, president of Amber Specialty Pharmacy, said in a press release. “We understand how important it is for at-risk individuals to have access to medication and reliable support in order to delay disease progression.

Related: FDA Approves First Drug that Delays Diabetes

The FDA approved Tzield last week. It will be available by the end of the year at a wholesale acquisition cost of $13,850 per vial for 14-day treatment course list price of $193,900, company executives said in a call with investors.

In October 2022 the company announced a co-promotion agreement for the U.S. launch of Tzield with Sanofi.