Insulin Therapy: Practical Clinical Aspects

While oral medications are the most common initial treatment of type 2 diabetes, oral monotherapy usually fails to control glucose levels over time. Findings have shown that after 3 years of monotherapy for type 2 diabetes, 50% of patients require combination therapy. After 9 years of monotherapy, that proportion rises to 75%. Nevertheless, even combination therapy eventually fails to control blood glucose levels in most patients. At this point, insulin therapy becomes necessary.