Ejection fraction is a key factor in how clinicians diagnose, classify and treat heart failure. But you might not know it if you depended solely on ICD-10 codes.
Tyler J. Gluckman, M.D., medical director of the Center for Cardiovascular Analytics, Research, and Data Science at Providence St. Joseph Health in Portland, Oregon, presented research findings this weekend at the American Heart Association Scientific Sessions meeting in Philadelphia about how well the ICD-10 codes used for billing and other purposes reflect ejection fraction.
Gluckman and his colleagues found a large variation in the ejection fraction among two of the most commonly used ICD-10 codes for heart failure, hypertensive heart disease with heart failure and hypertensive heart disease with heart failure and chronic kidney disease.
Ten patients have been treated with the CRISPR-based gene therapy, the drug developer's chief scientific officer announced today, and high doses have had the intended effect of lowering LDL cholesterol. One study volunteer died five weeks after the infusion from cardiac arrest, but the company says the death was unrelated to the therapy and no changes were made to the study.
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