FDA advisers recommend easing Avandia restrictions
July 25th 2013FDA advisers recommended in early June the easing of restrictions on the diabetes drug rosiglitazone (Avandia, GlaxoSmithKline), following an independent re-examination of GSK’s RECORD study conducted by Duke Clinical Research Institute.
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Telmisartan and valsartan present lower risk of heart attack and strokes in diabetes patients
July 24th 2013Telmisartan and valsartan, used to reduce blood pressure in people with diabetes, are associated with a lower risk of hospitalization for heart attack, stroke, or heart failure, according to a study published on the Canadian Medical Association Journal.
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Guideline adds aromatase inhibitor for breast cancer prevention
July 16th 2013The new update to the 2009 American Society of Clinical Oncology (ASCO) guideline on the pharmacologic interventions for breast cancer risk reduction now lists aromatase inhibitor exemestane (Aromasin, Pfizer) as an option for postmenopausal women for primary risk reduction that are at an increased risk of developing invasive breast cancer.
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Mobile app reminds patients to take their meds
July 15th 2013According to the World Health Organization, only 50% of patients living with a chronic illness take their medication on time as directed. An American dies every 19 minutes from skipping medication or taking meds incorrectly, costing US hospitals more than $100 billion every year.
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AREDS gets another look: Removing beta-carotene, adding lutein/zeaxanthin shows clear benefits
July 8th 2013Investigators had already determined that the Age-Related Eye Disease Study (AREDS) formulation slowed the progression to advanced age-related macular degeneration (AMD), with a 25% decrease in the likelihood of progression to advanced AMD compared with placebo.
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Underdosing in obesity-an epidemic: focus on antibiotics
July 4th 2013Obesity is associated with an increased risk of infection. Unfortunately clinical trials examining the safety and efficacy of antibiotics in obese patients are deficient. Thus, clinicians predominately rely on pharmacokinetic and pharmacodynamic data for appropriate antibiotic dosing. The current literature for vancomycin, aminoglycosides, beta-lactams, fluoroquinolones, linezolid, and macrolides was reviewed to evaluate appropriate dosing in obese patients. Due to the limited number of studies and various pharmacokinetic parameters of antibiotics, dosing should be based on both patient- and drug-specific factors.
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