Despite advancements, treatment of metastatic breast cancer hinges on multifarious factors and numerous unanswered questions about therapy linger. Agents that are highly active in heavily pretreated patients are needed to optimize outcomes in patients with metastatic disease. This article reviews current and novel treatment options for metastatic breast cancer.
FDA approved belimumab (Benlysta, Human Genome Sciences and GlaxoSmithKline) for the treatment of adult patients with active, autoantibody-positive systemic lupus erythematosus who are receiving standard therapy.
The managed care industry is missing a potentially rich opportunity to draw in consumers with the message that health insurance provides protection and peace of mind for the healthy as well as the sick.
States face huge budget deficits in the coming months, threatening their ability to maintain health, education and public safety programs.
It's not uncommon for bias and inaccuracies to infiltrate consumer health information and influence members' opinions about the healthcare they receive
Adults without health insurance are more likely to have undiagnosed hypercholesterolemia and hypertension than those with health insurance
With technology seemingly taking over the healthcare field, managed care organizations are thinking of innovative ways to reach out to consumers.
Blue Cross Blue Shield of Massachusetts has seen a rapid uptake of its new quality-based reimbursement structure
Forty-nine states have begun the activity necessary to have health insurance exchanges operational by 2014.
When major provisions of the Patient Protection and Affordable Care Act take place in 2014, MCOs will face new limits on premium rates in the individual and small-group markets.
Value is king. But in today's healthcare environment, value relies on refined quality measurements and innovative payment models.
Flexibility in response to market pressures has made PPOs the most popular type of managed care organization model.
Many states have to enact legislation authorizing the establishment of an exchange
FDA has approved ipilimumab (Yervoy, Bristol-Myers Squibb) to treat patients with late-stage (metastatic) melanoma, the most dangerous type of skin cancer.
FDA has approved an expanded age indication for Zoster Vaccine Live, (Zostavax, Merck) for the prevention of herpes zoster, commonly known as shingles, in adults ages 50 years and older.
The use of angiotensin-receptor blockers alone are not associated with increased odds of cancer or cancer-related death, according to a meta-analysis published in a recent edition of Lancet Oncology.
FDA and the European Medicines Agency have launched a new pilot program that will allow parallel evaluation of relevant development and manufacturing data components, known as Quality by Design, of new drug marketing applications that are submitted to both agencies.
Dabigatran etexilate mesylate (Pradaxa, Boehringer Ingelheim) capsules have received tier 2 formulary status with 2 key pharmacy benefit managers.
FDA released a safety communication to update prescribers and patients about the ongoing review of insulin glargine (Lantus) that was initiated in July 2009.
A substantial portion of antiretroviral-naïve patients are infected with transmitted drug-resistant HIV with one or more drug-resistant mutations, and they are much more likely to experience treatment failure, according to research published in The Lancet Infectious Diseases.
Patients with psoriatic arthritis undergoing their first treatment with tumor necrosis factor-? inhibitor showed a high adherence to therapy and a good response, according to a recent Danish study published in Arthritis & Rheumatism.
Many patients, especially those with limited literacy, do not consolidate prescription medication regimens efficiently, which could lead to nonadherence, according to a recent study in the Archives of Internal Medicine.
The willingness of the elderly to take medication for primary cardiovascular disease prevention is relatively insensitive to its benefit but highly sensitive to its adverse effects, according to a recent study published in the Archives of Internal Medicine.
The Indiana Health Information Exchange (IHIE) announced that its Quality Health First Program has enrolled more than 1,500 physicians in more than 50 communities
CareFirst, Inc., Owings Mills, Md., is launching a new Primary Care Medical Home (PCMH) program that takes aim at the chronically ill.
Open Health Market, a request for proposal (RFP) generation tool designed to allow employers of self-funded health plans to solicit and compare proposals directly from medical providers, is ready to launch.
XLHealth, a Baltimore-based provider of health plan solutions for Medicare beneficiaries with special needs, announced the enrollment of its 100,000th member, and it sees room for more growth despite expected Medicare Advantage cuts
FDA has approved a change to the prescribing information for ambrisentan 5-mg and 10-mg tablets (Letairis, Gilead Sciences) once-daily treatment to improve exercise ability and delay clinical worsening in patients with pulmonary arterial hypertension (PAH, WHO Group 1) and predominantly WHO Functional Class II-III symptoms.
The risk of certain birth defects is higher in women given opioid analgesics such as hydrocodone during pregnancy, according to a new study.
FDA recently announced its plans to remove certain unapproved prescription medicines used to treat cough, cold, and allergy symptoms.
