Rosanna Sutherby, Pharm.D.

Crohn's disease and ulcerative colitis can affect food intake and lead to malabsorption of nutrients and intestinal bacterial overgrowth.

Cerebral organoids shed light on cells that generate the myelin cells that protect the axons of neuron. In multiple sclerosis, inflammatory processes attack the myelin of neurons in the brain and spinal cord.

Some people with multiple sclerosis follow dairy-free or plant-based diets that may be low on calcium and vitamin D.

The classes with the strongest association with inflammatory bowel disease were those typically used to treat GI infections, nitroimidazoles and fluoroquinolones.

The new law raises the age threshold for the onset of disabling conditions that make people eligible to have the savings accounts. The money in the accounts do not count toward the limits for Medicaid and the Supplemental Nutritional Assistance Program.

Research by Maria T. Abreu, M.D., and Jacob McCauley, Ph.D., should help fill a gap in the research of the genetics of inflammatory bowel disease, including ulcerative colitis.

A Swedish and a French company have treatments with novel mechanisms of action in late-stage development. Meanwhile, AbbVie, Janssen and Eli Lilly are vying to get the first interleukin-23 inhibitor for ulcerative colitis on the market.

Spanish researchers found that progression of multiple sclerosis that was independent of relapses of the disease was associated with worse long-term outcomes.

A study by Kaiser Permanente researchers found that the overall the risk of COVID-19-related hospitalization was low in vaccinated individuals with multiple sclerosis, regardless of whether participants had received Rituxan treatment. Still, the findings suggest that spacing out vaccination may offer added protection against COVID-19.

Other adverse outcomes were not linked to histological inflammation, according to results of a Swedish study.

Researchers used a Fitbit Flex2 to examine the correlation between step counts and changes in the brain and spinal cord associated with multiple sclerosis.

Cobitolimod from InDex, a Swedish company, and obefazimod, from Abivax, a French company, could be first-in-class medications for ulcerative colitis.

Stomach acid interferes with the effectiveness of probiotics taken as pills. Researchers are bioengineering probiotics in hopes of getting around that problem.

Dozens of gene mutations associated with amyotrophic lateral sclerosis have been identified. Drug developers have homed in on a trio of genes.

Because vitiligo affects appearance, people with vitiligo are disproportionately affected by psychiatric conditions, including depression.

The melanocytes attacked by the autoimmune disease are present in the eyes and ears, not just the skin, so vitiligo can adversely affect vision and hearing.

German researchers developed a modified adeno-associated virus capsid that has greater affinity for liver cells.

Enyzyre says its at-home testing system will be a major advance for people with hemophilia because they will better able to manage the disease on their own.

CSL Behring's gene therapy, called EntranaDez, may be approved later this month. BioMarin, Pfizer, Bayer and Freeline Therapeutics also have gene therapies for hemophilia in development.

The tool successfully identified children with high asthma risk as young as 3 years of age. The screening tool was found to be more accurate at predicting asthma, persistent wheezing, and related emergency room visits and hospitalizations than standard screening and diagnostic tools.

Findings from research presented at the American College of Chest Physicians suggest the importance of selecting the right biologic from the start.

University of Wisconsin researchers find that people with asthma benefit from intervention that includes meditation and yoga and sustained focus on the breathing, thoughts, feelings, and bodily sensations.

Gilead’s magrolimab is the leading CD47 immune checkpoint inhibitor in development.

Several drugs with novel mechanisms of action have been put on the pathway for speedier approval decisions by the FDA. Phase 2 and 3 trials are underway.

Early interventions might preserve lung function, particularly in younger patients with frequent asthma exacerbations, say authors.

The hemophilia organization developed a shared decision-making tool for patients and providers.

Long-acting recombinant replacement factor gets favorable rating from multidisciplinary group. Gene therapy was viewed with some wariness.

Program in Hidalgo, Texas, cost less than $250 per family. A study found that the intervention saved each household an average of $36 per day.

A longitudinal study aims to identify which children with asthma are more likely to suffer a loss of lung function.

Findings suggest that screening people with hemophilia for diabetes and hypertension might have benefits.