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Jazz Pharmaceuticals Launches ALL Therapy Rylaze
The therapy is approved for both adults and children.
Jazz Pharmaceuticals has launched Rylaze (asparaginase erwinia chrysanthemi (recombinant)-rywn). The FDA approved Rylaze on June 30, 2021, as a component of a multi-agent chemotherapy regimen for the treatment of acute lymphoblastic leukemia (ALL) or lymphoblastic lymphoma (LBL) in adult and pediatric patients 1 month or older who have developed hypersensitivity to E. coli-derived asparaginase.
Rylaze was licensed from Ligand Pharmaceuticals.
The only other FDA-approved drug for such patients with allergic reactions has been under global shortage since 2016. Jazz Pharmaceuticals’ Erwinaze (asparaginase erwinia chrysanthemi) has experienced supply and manufacturing issues from the owner and manufacturer of the product, Porton Biopharma Limited. Jazz Pharmaceuticals’ agreement with Porton Biopharma ended in December 2020.
In May 2021, the FDA had authorized Porton Biopharma and its distributor Clinigen to import Erwinase (crisantaspase) into the United States and bring this therapy to physicians.
Jazz licensed Rylaze from Ligand Pharmaceuticals, which received a $2 million payment when the FDA accepted the BLA for review and is entitled to receive a $5 million payment upon the first commercial sale following launch.
Using the 'Pathway' Approach to Shorten the Time Between Cancer Diagnosis and Treatment
November 16th 2022In this episode of Tuning In to the C-Suite, Briana Contreras, editor with Managed Healthcare Executive spoke with Dr. Yuri Fesko, oncologist and vice president of Medical Affairs at Quest Diagnostics. In the conversation, Dr. Fesko addressed the ongoing issue of long gaps of times between receiving a diagnosis for a type of cancer and finally getting the treatment for it. Dr. Fesko shared the benefits a number of sectors receive when treating patients sooner and the steps to get there.
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