No safety issues observed with combination treatment for recurrent herpes simplex labialis
December 27th 2010Treatment of recurrent herpes simplex labialis with combination 5% acyclovir and 1% hydrocortisone cream is safe in adolescents. In a study of a 5-day treatment course, no safety concerns were identified, said Anders Strand, MD, PhD, at the 45th midyear meeting of the American Society of Health Systems Pharmacists, in Anaheim, Calif.
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More reduction in LDL cholesterol lessens vascular events
December 27th 2010Further reductions in LDL cholesterol with more intensive statin regimens safely produce definite further reductions in vascular events, even down to very low LDL levels, lower than current targets, according to the results of 2 meta-analyses, as reported Nov. 8 online by The Lancet.
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FDA approves CNS Therapeutics' baclofen injection drug for severe spasticity
December 20th 2010CNS Therapeutics announced that FDA has approved baclofen injection (Gablofen) for use in the management of severe spasticity. The drug gives providers an easy-to-administer, cost-effective intrathecal baclofen treatment option, according to the company.
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FDA approves CNS Therapeutics' baclofen injection drug for severe spasticity
December 20th 2010CNS Therapeutics announced that FDA has approved baclofen injection (Gablofen) for use in the management of severe spasticity. The drug gives providers an easy-to-administer, cost-effective intrathecal baclofen treatment option, according to the company.
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Kombiglyze XR tablets approved for the treatment of type 2 diabetes mellitus in adults
December 20th 2010FDA has approved saxagliptin and metformin XR (Kombiglyze XR, AstraZeneca and Bristol-Myers Squibb) tablets for the treatment of type 2 diabetes in adults. Kombiglyze XR is the first and only once-a-day metformin XR plus DPP-4 inhibitor combination tablet offering strong glycaemic control across glycosylated hemoglobin levels, fasting plasma glucose and post-prandial glucose.
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Local healthcare reform implements treatment processes
December 15th 2010Findlay, Ohio is one of the first communities in the United States to establish a partnership between area businesses, physicians and the local hospital to initiate healthcare reform at the community level. The program, called the Employer Data Project (EDOC), is overseen by Blanchard Valley Health System (BVHS). Its goal is to reduce variation in care and improve treatment processes while lowering health care costs.
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Disease management outcomes measurement requires mathematical proof
December 15th 2010The Disease Management Purchasing Consortium (DMPC) and Zenger Analytics have completed a mathematical proof to address the question of valid outcomes methodologies for disease management, wellness, medical home and other population-based care management programs for which outcomes are calculated on a pre/post basis.
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FDA panel recommends approval of weight-loss drug
December 9th 2010An FDA panel has recommended that the agency approve Orexigen Therapeutics' and Takeda's obesity drug Contrave (naltrexone SR/bupropion SR). This makes the drug the first in a group of competitors to receive this recommendation, the Associated Press reported.
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Therapy Update: Nonanthracycline regimens for adjuvant treatment of operable breast cancer
December 7th 2010Nonanthracycline-containing chemotherapy regimens for the adjuvant treatment of operable stage I to III breast cancer are discussed, including efficacy and toxicity results from recent randomized clinical trials comparing anthracycline to nonanthracycline-containing regimens.
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Study finds acetaminophen increases blood pressure in patients with coronary artery disease
December 1st 2010The commonly used pain reliever-acetaminophen-causes a significant increase in blood pressure in patients with pre-existing coronary artery disease, according to a randomized controlled trial published ahead of print in the October 18, 2010, Circulation.
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Focus on 2010: A year of novel pharmacologic agents in review
December 1st 2010Throughout 2010, Formulary's "Focus on" articles have examined 10 newly approved or investigational drugs of interest to pharmacy and therapeutics (P&T) committee members. Because many readers have said that they frequently refer to this column when making formulary decisions for hospitals, health systems, or managed care organizations, the editors have compiled this review of these agents, along with updates on the regulatory status of each.
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Patients with systolic heart failure and mild symptomatology [New York Heart Association class II] taking the mineralocorticoid receptor antagonist-eplerenone-experienced a 37% reduction in death from cardiovascular causes or first hospitalization for heart failure, researchers demonstrated in a new study.
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