• Hypertrophic Cardiomyopathy (HCM)
  • Vaccines: 2023 Year in Review
  • Eyecare
  • Urothelial Carcinoma
  • Women's Health
  • Hemophilia
  • Heart Failure
  • Vaccines
  • Neonatal Care
  • NSCLC
  • Type II Inflammation
  • Substance Use Disorder
  • Gene Therapy
  • Lung Cancer
  • Spinal Muscular Atrophy
  • HIV
  • Post-Acute Care
  • Liver Disease
  • Pulmonary Arterial Hypertension
  • Biologics
  • Asthma
  • Atrial Fibrillation
  • Type I Diabetes
  • RSV
  • COVID-19
  • Cardiovascular Diseases
  • Breast Cancer
  • Prescription Digital Therapeutics
  • Reproductive Health
  • The Improving Patient Access Podcast
  • Blood Cancer
  • Ulcerative Colitis
  • Respiratory Conditions
  • Multiple Sclerosis
  • Digital Health
  • Population Health
  • Sleep Disorders
  • Biosimilars
  • Plaque Psoriasis
  • Leukemia and Lymphoma
  • Oncology
  • Pediatrics
  • Urology
  • Obstetrics-Gynecology & Women's Health
  • Opioids
  • Solid Tumors
  • Autoimmune Diseases
  • Dermatology
  • Diabetes
  • Mental Health

Sleep Restriction is More Stressful Than Sleep Fragmentation

Article

Researchers compared cardiac effects of waking people up every hour to limiting them to five hours of sleep.

Sleep restriction but not sleep fragmentation increases the “fight or flight” response and could have negative effects on the heart, according to a study published yesterday in Scientific Reports.

A team of German researchers recruit 20 healthy male volunteers (average age 40.6) to participate in a study that involved one night of sleep fragmentation during which they slept for eight hours but were woken up seven times by turning on a light on every hour. Another night their sleep was restricted to five hours (11 p.m. to 4 a.m.). The two intervention nights were separated by two recovery days and an 11-day “wash out” periods. The researchers, led by Julia Schlagintweit, used electrocardiography to measure heart rate and heart rate variability.

They found no significant difference in the cardiac activity during the fragmentation night and measurements during a baseline period. However, the measurements during the restriction intervention showed cardiac activity that is seen during the activated fight-or-flight response.

“Sleep restriction influences cardiac autonomic tone more than sleep fragmentation,” Schlaginweit and her colleagues concluded, using the term for part of the nervous system that regulates physiologic processes such as the heart rate and blood pressure. There is a shift toward higher “sympathetic” activity that is the fight-or-flight response and lower “parasympathetic activity,” or vagal activity, which occurs when the body is in a “rest and digest” mode, they wrote.

“This indicates,” they said, “that sleep restriction may cause more stress for the organism than a sleep fragmented night.”

Related Content
© 2024 MJH Life Sciences

All rights reserved.