Opinion|Videos|November 10, 2025

Prevalence of Decreased eGFR and Elevated uACR

Expert discusses how the high prevalence of undiagnosed CKD creates a significant clinical and financial burden that can be alleviated through earlier detection and intervention.

Expert discusses how the prevalence of chronic kidney disease (CKD), as reflected by decreased estimated glomerular filtration rate (eGFR) and elevated urinary albumin-to-creatinine ratio (uACR) levels, represents a widespread but often silent health issue. Many individuals remain undiagnosed until the disease has advanced, leading to avoidable complications and hospitalizations. This underrecognition contributes to significant public health challenges, including late interventions and greater progression to kidney failure.

Expert discusses how this burden extends beyond patients to the entire health care system. Individuals with CKD often require frequent monitoring, specialist referrals and complex medication regimens. The associated costs — hospital readmissions, dialysis and cardiovascular events — strain health care resources, making early detection an economic as well as clinical priority.

Expert discusses how improved screening and early-stage recognition can mitigate these burdens. Raising awareness among clinicians and payers about the prevalence of decreased eGFR and elevated uACR helps drive earlier intervention and resource allocation, ultimately improving long-term patient outcomes.

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