The price for of Adbry is $1,810.87 for a two pack of syringes.
The FDA has expanded the approval of Leo Pharma’s Adbry (tralokinumab-ldrm) to include pediatric patients aged 12 to 17 years with moderate-to-severe atopic dermatitis (AD). It’s indicated for patients whose disease is not adequately controlled with topical prescription therapies. Adbry is already approved for patients 12 years of age and older.
Adbry is a biologic that specifically binds to and inhibits the interleukin (IL)-13 cytokine, one of the key drivers of atopic dermatitis signs and symptoms. For the 12- to 17-year-old patient population, the initial dose of 300 mg is followed by a 150 mg dose every two weeks.
The price of Adbry is $1,810.87 for a two-syringe pack; a pack of four syringes has a price of $3,621.73, according to a company spokesperson.
Leo offers several programs, include a $0 copay program for those with commercial insurance, a bridge program for insured patients whose insurance does not yet cover Adbry, as well as a patient assistance program for those without insurance.
Atopic dermatitis is a chronic, inflammatory skin disease characterized by intense itch and lesions. IL-13 has been identified as a key cytokine that plays an important role in atopic dermatitis. There are an estimated 2.4 million patients aged 12 to 17 years of age in the United States living with atopic dermatitis, with about half moderate-to-severe disease.
The approval in the pediatric population is based on data from the phase 3 ECZTRA 6 trial, which evaluated the efficacy and safety of Adbry in 289 patients aged 12 to 17 years of age. In the trial, more than five times as many pediatric patients had clear or almost clear skin with Adbry compared with placebo, and about seven times as many pediatric patients experienced significantly reduced itch with Adbry compared with placebo.
Data from ECZTRA 6 was presented in March 2023 at the American Academy of Dermatology (AAD) 2023 Annual Meeting.
Get the latest industry news, event updates, and more from Managed healthcare Executive.
PBM-Offered Genomics Testing Could Reshape Prescribing of Medications
July 25th 2025Two PBMs, True Rx Health Strategies and Capital Rx, are using pharmacogenomics — how a person’s DNA affects their response to medications — to reduce the trial-and-error of prescribing medications, saving employers and patients time and money.
Read More
In this episode of the "Meet the Board" podcast series, Briana Contreras, Managed Healthcare Executive editor, speaks with Ateev Mehrotra, a member of the MHE editorial advisory board and a professor of healthcare policy and medicine at Harvard Medical School. Mehtrotra is also a hospitalist at the Beth Israel Deaconess Medical Center in Boston. In the discussion, Contreras gets to know Mehrotra more on a personal level and picks his brain on some of his research interests including telehealth, alternative payment models and price transparency.
Listen
FDA Extends Review of Blenrep Combinations in Multiple Myeloma
July 24th 2025Last week, an FDA advisory committee against the risk-benefit profile of Blenrep in combination with other therapies. Regulators and reviewers were concerned about the ocular side effects and dosing and tolerability. The new action date is Oct. 23, 2025.
Read More
Sarepta to Pause Shipments of the Gene Therapy Elevidys
July 22nd 2025Sarepta officials said the temporary halt in shipments was done to maintain a productive working relationship with regulators while they address a safety labeling update about the risk of acute liver disease related to Elevidys.
Read More