News

Gastric bypass surgery can improve glycemic control in adults with type 2 diabetes, but doesn't cure diabetes, according to the largest community-based study of long-term diabetes outcomes after bariatric surgery, published online ahead of print in Obesity Surgery.

Linzess (Linaclotide)

New molecular entity: FDA approved linaclotide (Linzess, Ironwood Pharmaceuticals and Forest Pharmaceuticals) for the treatment of chronic idiopathic constipation and irritable bowel syndrome (IBS) with constipation in adults.

Pipeline Preview

Recent FDA action (through December 2012) related to, Rabeprazole sodium delayed-release sprinkle capsules, CXA-201, CB-215, Buprenorphine subdermal implant, LX1033, ISIS-TTR Rx, Digoxin Immune Fab, Glucagon, AAV1-FS344, Trans sodium crocetinate, Betamethasone valerate foam 0.12%

African-American men and women continue to have higher risks of dying at the first presentation of heart disease compared with their white counterparts, according to a study published in the Journal of the American Medical Association.

Recent FDA Approvals (through December 2012) related to (Bedaquiline, Janssen, Oseltamivir, Genetech, Apixaban, Bristol-Myers Squibb, Lomitapide, Aegerion, Varicella zoster immune globulin preparation, Cangene, Teduglutide, NPS Pharmaceuticals, Pasireotide diaspartate, Novartis, Ponatinib, ARIAD Pharmaceuticals, Influenza virus vaccine, GlaxoSmithKline, Raxibacumab, Crofelemer, Salix, Cabozantinib, Exelixis)

Last week, NABP Executive Director Carmen Catizone, MS, RPh, unveiled an action plan to inspect nonresident compounding pharmacies and create a database to share regulatory information about these pharmacies with the state boards of pharmacy nationwide. This was in response to the fungal meningitis outbreak that took the lives of 37 individuals and injured 590.

When men are treated for a longer-duration antibiotic therapy for urinary tract infection (UTI), there is no decrease in early recurrence compared with those treated for a shorter duration, according to a study online in Archives of Internal Medicine.

Half of the 3.2 billion prescriptions dispensed annually are not taken as prescribed. Pharmacy benefit leaders must reconsider the financial context of medication adherence and medication possession, according to industry leaders presenting at a recent online seminar for the Pharmacy Benefit Management Institute.

Diabetic patients with ovarian cancer who took the drug metformin for their diabetes had a better survival rate than patients who did not take it, according to a study from Mayo Clinic, published early online in Cancer.

Osteoporosis medication is also effective in men, according to a large-scale, international study, published in a recent issue of the New England Journal of Medicine.

Pipeline Preview

Recent FDA action (through November 2012) related to, H5N1 adjuvanted influenza vaccine, Pasireotide, Digoxin immune fab, Etirinotecan pegol, OBI-1, beclomethasone 17, 21-dipropionate, Regorafenib, Trastuzumab emtansine, A4250, Sildenafil

Individuals with high cholesterol who stay on their statin medications over a 2-year period are healthier than comparable nonadherent individuals, but the overall cost of their care is slightly higher, according to a new study presented at the Academy of Managed Care Pharmacy 2012 Education Conference, in Cincinnati, Ohio, in October.