The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) has prematurely terminated a trial of sildenafil for the treatment of pulmonary arterial hypertension (PAH) in adult patients with sickle cell disease because of safety concerns.
After completing an analysis of safety data for tumor necrosis factor (TNF)-blockers, FDA has stated that there is an increased risk of lymphoma and other cancers in pediatric patients who are treated with these agents.
Lundbeck and Solvay have announced that they are discontinuing development of bifeprunox for the maintenance treatment of schizophrenia.
Lilly and BioMS Medical reported that their investigational agent dirucotide did not meet the primary end point of delaying disease progression in patients with secondary progressive multiple sclerosis (SPMS) in the phase 3 MAESTRO-01 trial.
A study published in Urology demonstrated that alpha-blocker use is associated with a lower risk of sexual dysfunction in men aged >40 years.
Initiation of antipsychotic therapy associated with hyperglycemia in older diabetic patients
With healthcare-reform legislation moving forward, insurers, providers, and pharmaceutical companies are keeping a sharp eye on policy proposals likely to affect coverage, costs, and benefits. Various constituencies in the healthcare community are supporting initiatives that will increase access to healthcare and make the nation's costly healthcare system more efficient and effective.
The rate of hospitalizations that involved an injury likely due to osteoporosis increased 55% since 1995, to just more than 254,000 hospital stays totaling $2.4 billion in hospital costs in 2006, according to AHRQ.
Activity and progress increase on the exchange of health information electronically between physicians, hospitals, plans and patients, while cost savings have been identified.
AHIP healthcare reform ads touted as one that will resonate with many Americans.
The University of Miami and technology partners Microsoft and Resolute Solutions Corp. are teaming up to see if patients with diabetes can self manage their disease virtually while replicating the traditional patient-provider relationship.
Bayonne Hospital Center-Horizon Blue Cross Blue Shield of New Jersey heats up.
UnitedHealthcare's acquisition of Health Net's NE licenses and rights to renew membership underscores that scale in local markets is an important asset as companies pursue growth and local focus is key.
Like other health insurers before it, Aetna considers selling off its PBM unit.
In a retrospective analysis published in the journal Neurology, investigators demonstrated that previous treatment with intravenous immunoglobulin (IVIg) was associated with a reduced risk of the development of Alzheimer's disease and related disorders (ADRD) in patients aged at least 65 years.
This review discusses emerging risk factors for CVD, including hs-CRP, lipoprotein(a), homocysteine, fibrinogen, homocysteine, and coronary artery calcification.
Rivaroxaban is a highly potent direct factor Xa inhibitor that is pending FDA approval for the indication of venous thromboembolism (VTE) prophylaxis in patients undergoing total knee replacement or total hip replacement surgery.
Recent FDA action (through August 2009) related to trazodone, casopitant, sertindole, alogliptin, bepotastine, trabectedin, and velaglucerase alfa
Generic drug approved by FDA (through August 2009): ethinyl estradiol/norgestimate tablets
New molecular entity: Dronedarone (Multaq), a benzofuran derivative, was approved on July 1, 2009, to reduce the risk of CV hospitalization in patients with AF
New molecular entity: Prasugrel (Effient), a platelet activation and aggregation inhibitor, was approved on July 10, 2009, to reduce the rate of thrombotic CV events in patients with ACS undergoing PCI
Agents in late-stage development for the treatment of osteoarthritis and acute/chronic pain
Proactive organizations will begin a painful transition to emerge as larger, fuller enterprises with concentrated authority designed around very different roles and responsibilities than what they have today
Collaborative healthcare communities gather clinical and claims data to apply to real-world settings
Dean Health Plan and its PBM business seek sure footing for today's changing times in healthcare
Discussing hospice and palliative care with patients and families lowers healthcare costs and allows patients to realize maximum benefits of care
Outcomes-based contracting enables risk sharing between plans and manufacturers while also allowing better patient adherence to regimens
The United Kingdom implemented ICD-10 as far back as 1995, making the United States one of the last major global economies to begin the implementation process.
Straying from the popular opinion of the industry, a handful of medical device manufactures have aligned with Obama's proposed investment in comparative effectiveness research.
If these programs are executed correctly, they can educate patients about their medications, provide physicians with information about the effectiveness of drugs and facilitate communication
