A panelist discusses how type 1 diabetes (T1D) is a complex autoimmune disease characterized by progressive beta cell destruction that advances through distinct stages, with genetic predisposition, environmental triggers and the presence of specific autoantibodies serving as key risk factors and diagnostic markers.
A panelist discusses how C-peptide serves as a critical biomarker of endogenous insulin production, providing clinicians with valuable insights into remaining beta cell function that can guide personalized treatment approaches and help predict disease progression in patients with type 1 diabetes (T1D).
A panelist discusses how autoimmune screening through detection of diabetes-specific autoantibodies serves as a critical tool for identifying pre-symptomatic type 1 diabetes (T1D), enabling earlier intervention before significant beta cell loss occurs and potentially changing the disease trajectory through timely management strategies.
A panelist discusses how type 1 diabetes (T1D) is frequently misdiagnosed in adults due to its overlapping clinical features with type 2 diabetes (T2D), resulting in inappropriate treatment strategies that fail to address the autoimmune destruction of beta cells and lead to accelerated disease progression and complications.
A panelist discusses how preserving beta-cell function in type 1 diabetes (T1D) requires a multifaceted approach combining timely diagnosis, immunomodulatory therapies, optimal glycemic control and emerging technologies that can slow disease progression and improve patient outcomes.
A panelist discusses how the adoption of C-peptide preservation as a critical end point in clinical trials represents a paradigm shift in type 1 diabetes (T1D) research, moving beyond glucose control alone to focus on disease-modifying therapies that can maintain endogenous insulin production and potentially alter the fundamental course of the disease.
