Looking for links between atopic dermatitis and ADHD
Researchers found an association between ADHD and three inflammatory conditions—atopic dermatitis, otitis media, and herpes simplex infection.
Why Do Women With Heart Failure Have Poorer Quality of Life?
Using AI to improve ECG data capture on portable devices
Training an AI model to identify LVSD from single-lead ECG data would allow more reliable, earlier diagnosis.
Newly Discovered Genes Could Change Vitiligo Treatment
Scientists say it could lead to new drugs for vitiligo and other pigmentation diseases.
Post-hoc Findings From Inpefa Trial Show Benefit of Starting Drug Before Discharge
Results show that the new heart failure drug reduces the hospitalizations and risk of death from cardiovascular events.
The Booming Market for Atopic Dermatitis Drugs
The US accounted for nearly half of the atopic dermatitis drugs market in 2021. According to 2021 data from the National Center for Health Statistics, roughly 7% of adults in the U.S. have eczema.
Using 3D Technology To Mimic Human Skin
Mayo Clinic researchers have developed a process that uses human cells as inks, dubbed bioinks, to print natural tissue-like structures in three dimensions.
Redlining Heart Failure
Two studies show that high heart failure rates in the Black population are a legacy of discriminatory mortgage policies.
The Link between a Happy, Healthy Community and Cardiovascular Disease Mortality
New Study Aims to Decipher the Mystery of Vitiligo
The study will enroll an estimated 1,000 patients, of whom approximately 200 will have vitiligo. The remaining participants will be at-risk family members, some 40 to 60 of whom are expected to develop vitiligo during the 5-year study.
Biocardia Pauses Trial of Innovative Stem Cell Therapy
The pause was recommended by an independent data safety monitoring board, according to a company press release.
When Statins Aren’t the Answer, Bempedoic Acid Could Be
A study in statin-intolerant patients suggests that bempedoic acid reduces the risk of major cardiovascular events significantly.
Seeing Skin Disease From Both Sides
Results reported in JAMA Dermatology today show disagreement between physicians and patients in the grading of skin disease. Physicians tend to see severity relative to other patients, note the researchers, while patients may compare themselves with peers and their social circle.
American Academy of Dermatology Updates Guidelines on Atopic Dermatitis Treatments
The guidelines strongly recommend topical corticosteroids for adults, as well as the intermittent use of medium-potency topical corticosteroids as maintenance therapy (two times per week) to reduce disease flares and relapse.
For Alecensa, ‘Take With Meal’ May Have a Caveat
Study suggests that low-fat meals may affect blood concentration levels, and high blood concentration has been correlated with a better response to the drug.
‘Thrilling’ Finding: Daily Tagrisso Halves Risk of Death in Some Lung Cancer Patients
Findings from the ADAURA trial argue for starting treatment with the AstraZeneca drug early, says Yale’s Roy Herbst, M.D., Ph.D., the principal investigator.
What’s The Best Treatment for VTE in Cancer?
In a clinical trial, researchers concluded that direct oral anticoagulants were non-inferior to low-molecular-weight heparin.
New Predictors of Length of Stay for Heart Failure Patients
Some factors found in previous investigations, such as stroke, were not significant in this study, while treatment interruption and severe tricuspid valve regurgitation were newly identified.
Whey Protein For Building Muscle in Heart Failure Patients
Positive results from a small study suggest that whey protein could have some benefits for people with heart failure, although it is a preliminary finding. Whey protein has a high concentration of leucine, which may help build muscle.
Cardiovascular Risk Factors, Cognitive Decline Are Linked
Study shows that every 5% increment in the cardiovascular disease risk as measured by the 10-year Framingham risk score was related to lower cognitive function.
Investigating the Link Between Exposure to Second-hand Smoke and Childhood Myopia
Exposure to second-hand smoke may be more harmful for young children than adults because of their faster respiratory rate.
Clues to the Complex Pathogenesis of Glaucoma
Researchers using data from prospective cohort studies identify higher levels of diglycerides and triglycerides in the blood as possibly playing an important role in the multifactorial causation of glaucoma.
Diabetic Retinopathy on the Decline Among Native Americans
Findings reported in JAMA Opthalmology show substantial decrease from 30 years ago.
Reprogramming Tumor Cells
Researchers in Spain explore strategies for making tumor microenvironment less “tumor permissive.” Their experiments were in mice models of the lung cancer, so the findings are from early-stage research and far from the final word.
Fimepinostat May Prolong Survival in SCLC
The findings provide evidence that the MYC family of oncogenes is a driver of resistance.
First-line Immune Checkpoint Inhibitors May Have Lower Risk of Hyperprogression
Study of patients treated with Tecentriq (atezolizumab) shows the risk of hyperprogression is .7% when the PD-L1 is used as a first-line therapy and 8.8% when it was used in later lines of therapy.
Depression in NSCLC is a Key Indicator of Outcomes
Researchers find an association between depression and biomarkers for inflammation, which may mean a poor prognosis.
Reducing the Risk of Severe Radiation-induced Lymphopenia
South Korean researchers report results that show pencil-beam scanning proton therapy may lower the risk of severe radiation-induced lymphopenia in people treated for lung cancer.
First Double-Lung Transplants in Advanced Lung Cancer
Risk of Retinal Vascular Occlusion After COVID-19 Vaccination
Study shows the risk after COVID-19 vaccination is comparable to risk after flu and Tdap vaccine, and that the risk from COVID-19 infection is much greater.
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