• Hypertrophic Cardiomyopathy (HCM)
  • Vaccines: 2023 Year in Review
  • Eyecare
  • Urothelial Carcinoma
  • Women's Health
  • Hemophilia
  • Heart Failure
  • Vaccines
  • Neonatal Care
  • Type II Inflammation
  • Substance Use Disorder
  • Gene Therapy
  • Lung Cancer
  • Spinal Muscular Atrophy
  • HIV
  • Post-Acute Care
  • Liver Disease
  • Pulmonary Arterial Hypertension
  • Biologics
  • Asthma
  • Atrial Fibrillation
  • Type I Diabetes
  • RSV
  • COVID-19
  • Cardiovascular Diseases
  • Breast Cancer
  • Prescription Digital Therapeutics
  • Reproductive Health
  • The Improving Patient Access Podcast
  • Blood Cancer
  • Ulcerative Colitis
  • Respiratory Conditions
  • Multiple Sclerosis
  • Digital Health
  • Population Health
  • Sleep Disorders
  • Biosimilars
  • Plaque Psoriasis
  • Leukemia and Lymphoma
  • Oncology
  • Pediatrics
  • Urology
  • Obstetrics-Gynecology & Women's Health
  • Opioids
  • Solid Tumors
  • Autoimmune Diseases
  • Dermatology
  • Diabetes
  • Mental Health

Rating Drugs in the Pipeline | 2023 Annual Managed Healthcare Executive Pharmacy Survey


Roctavian (valoctocogene roxaparvovec), the gene therpay for hemophilia A, gets nods as holding the most promise among the drugs in the pipeline.

Roctavian (valoctocogene roxaparvovec), the gene therpay for hemophilia A, gets nods as holding the mRoctavian (valoctocogene roxaparvovec), the gene therpay for hemophilia A, gets nods as holding the most promise among the drugs in the pipeline.ost promise among the drugs in the pipeline.

Payers, providers, pharmaceutical companies all keep an eye on the “drug pipeline,” industry shorthand for drugs in mid- and late-stage development. FDA approval is a finish line and 14 new drugs have crossed that threshold so far this year, including the Leqembi (lecanemab), a new Alzheimer’s drug, in January, and just last week, Qalsody (tofersen), a drug for a small minority of people with amyotrophic lateral sclerosis who have certain gene changes.

The 2023 Annual Managed Healthcare Executive Pharmacy Surveyasked respondents to rate which drugs “hold the most promise” among several in the much-heeded pipeline. Valoctocogene roxaparvovec, a gene therapy for hemophilia A, garnered the most support (33%). The FDA is currently expected to announce whether it has approved on June 30. BioMarin Pharmaceutical Inc. is planning to market valoctocogene roxaparvovec under the brand name Roctavian.

After Roctavian, 27% of the 311 respondents ranked zuranolone, a treatment for major depressive disorder and postpartum depression, as holding the most promise, followed by the vaccines for respiratory syncytial virus (17%), tirzepatide, marketed as Mounjaro, for weight loss (16%) and resmetirom (6%), a new drug for nonalcoholic steatohepatitis, or NASH.

The survey also asked respondents to which gene therapies will have the most significant impact. Zynteglo (betibeglogene autotemcel) for beta thalassemia garnered the most selections, followed by Hemgenix (etranacogene dezaparvovec) for hemophilia B, Skysona (elivaldogene autotemcel) for cerebral adrenoleukodystrophy and Adstiladrin (nadofaragene firadenovec) for bladder cancer.

The online survey was conducted Feb. 14-28. The respondents were spread fairly evenly across the various sectors of the U.S. healthcare industry, with 20% self-identifying as working for hospitals, 22% for physician practices, 19% for pharmacy benefit managers, 16% for payer organizations, 13% for drug and device manufacturers and the rest in a variety of sectors.

Related Videos
Video 8 - "Demographic Differences That Impact Care"
Video 7 - "Gaps in Diabetes Education and Self Efficacy"
Video 6 - "Developing Reimbursement Models for Digital Therapeutics"
Video 5 - "Cost-Effectiveness Metrics Payers Seek for Digital Therapeutics"
Video 2 - "Bridging Care Gaps with Prescription Digital Therapeutics"
Video 1 - "Overview of Prescription Digital Therapeutics and Impact on Clinical Practice"
Video 4 - "Payer Challenges in Evaluating Digital Therapeutics"
Video 3 - "Industry Collaboration in Shaping Digital Therapeutics Standards"
Video 6 - "Key Takeaways and Unmet Needs in Diabetes Treatment"
Video 5 - "Allocation of Investment and Value-Based Arrangements in Diabetes Care "
Related Content
© 2024 MJH Life Sciences

All rights reserved.