Etravirine is an HIV-1 specific, non-nucleoside reverse transcriptase inhibitor (NNRTI) that was FDA approved for treatment-experienced adult patients with HIV-1 strains resistant to an NNRTI and other antiretroviral agents. In phase 3 trials of etravirine versus placebo, both in combination with darunavir/ritonavir, a background of nucleoside/nucleotide reverse transcriptase inhibitors with or without enfuvirtide demonstrated potent antiviral activity that was sustained through 48 weeks.
The main objectives of gout therapy are to treat the acute attack, provide prophylaxis to prevent flares, and prevent complications associated with the deposition of urate crystals in tissues. Obesity, alcohol intake, and certain foods and medications can contribute to hyperuricemia and should be identified. Pharmacologic management remains the mainstay of treatment for chronic gout and acute attacks.
Recent FDA action (through March 2010) related to CPI-300, Ondansetron, Intravenous acetaminophen, Gabapentin enacarbil, Rifaximin, ENMD-2076, Ap301, CM-AT, Fingolimod, Nilotinib.
On February 18, 2010, FDA recommended drastic changes in the way long-acting beta2-adrenergic agonists are used in the treatment of asthma in order to limit their utilization.
Our current system puts private, third-party payers in a key position, because they provide the financial incentives that drive behavior through a large portion of the healthcare system.
Whether your organization has health information technologies (HIT) in place today or preparations for meaningful use are just beginning, the time is now to understand your environment, locate where patient information exists today and prioritize your needs.
In the alphabet soup of healthcare, nothing's garnering greater attention these days than accountable care organizations.
Timely access to treatment for HMO patients in California has been a long time in coming as HMOs, physicians, hospitals, and consumer groups battled it out.
Deborah Peel, MD, knows patient data can be protected as well as leveraged for analytical research, but the infrastructure must be redesigned for granular control
Anthem Blue Cross says that rising healthcare costs in a challenging economy necessitate higher premiums.
Providers that have not adopted EHRs that meet the meaningful use standards of the Health Information Technology for Economic and Clinical Health Act by 2015 face a significant decrease in Medicare reimbursement.
It's intuitive that preventing a problem from happening is preferable to fixing it after the fact.
Blue Cross Blue Shield of Michigan and 15 hospitals will embark on a statewide project in May to cut the millions of dollars spent on preventable hospital readmissions.
Public spending is projected to total more than $1.2 trillion in 2010 and to account for slightly more than 50% of all national health expenditures in 2011.
Employee wellness programs are becoming a mainstream perk at many larger companies, but whether they're worth the time and effort depends on whom you ask.
The need to improve the accessibility and efficiency of healthcare has more providers adopting the emerging shared medical appointment model.
As the baby boom generation ages, more and more employees are taking on a second job as caregivers to elderly parents or chronically ill relatives.
Health IT will enable a sweeping transformation.
Just as national health reform fervor began to wane in Washington in recent weeks, California's state senate approved a bill to create a $200 billion, single-payer, government-run state health system. Ugh.
There are pros and cons of posting UM criteria online. Information can be helpful, but it can also open up a can of worms.
Costs for the most popular types of healthcare coverage are projected to increase at double-digit rates for 2010.
Cardiovascular disease is the greatest health threat to women in the United States.
Heterogenity is a huge hurdle for healthcare organizations that hope to capitalize on the wealth of data they possess.
A health plan's approach to provider reimbursement is rooted in the need to move from traditional fee-for-service models to a payment model that accounts for providers adhering to best practices.
Insurance exchanges will not exist in a vacuum; they will touch every part of the healthcare system and require substantial changes to the way payers do business.
UnitedHealthcare has completed the acquisition of the Northeast's licensed subsidiaries of Health Net and has obtained rights to renew Health Net's membership in Connecticut, New York and New Jersey.
As patient access to electronic medical records takes shape, many questions remain.
CIGNA International will develop and offer individual private medical insurance (PMI) for citizens in countries outside the United States as well as to individual expatriates and high net worth individuals.
A study recently conducted by US Oncology and Aetna found that evidence-based care for patients with non-small cell lung cancer (NSCLC) resulted in an average cost savings of 35% over 12 months while demonstrating equivalent health outcomes.
Currently, exenatide is the only FDA-approved GLP-1 receptor agonist and its use is limited by the need for twice-daily injections. A long-acting release formulation of exenatide is being evaluated in clinical trials to assess effects on glucose control and patient quality of life.
