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Covid-19 Antibodies Found in Nonimmune Blood Cancer Patients After Receiving Booster
Patients with blood cancers have been reported to have less of a chance to develop immunity from the COVID-19 vaccination. However, new data has been found stating those who have been previously vaccinated with no immunity and then followed up with a booster dose, eventually developed antibodies against the virus.
Patients with blood cancers have been reported to have less of a chance to develop immunity from the COVID-19 vaccination. However, new data has been found stating those who have been previously vaccinated with no immunity and then followed up with a booster dose, eventually developed antibodies against the virus.
This data is based off of a study that was published in July in the American Cancer Society's journal, Cancer.
Authors of the study retrospectively analyzed serologic responses to initial and booster COVID-19 vaccination in 378 patients with hematologic malignancy, or blood cancers such as leukemia, lymphoma and multiple myeloma, and subsequently tracked COVID-19–related outcomes.
Antibodies were found in 181 patients after initial vaccination; patients who had active malignancy or those who were recently treated with a B-cell–depleting monoclonal antibody had the lowest rates of developed antibodies, the study said.
For initial nonresponders to the vaccination, immunity after a booster dose occurred in 48 of 85 patients (56%). The seroconversion or immunity rate after the booster was similar for patients on (53%) and off (58%) active therapy.
Results from the study also found 33 patients (8.8%) developed a COVID-19 infection, and three succumed to COVID-19–related deaths (0.8%).
Researchers found that post-vaccination antibody response may not be associated with a decrease in any COVID-19 infection. They suggested effective vaccination with a booster, supplemented by passive immunization using tixagevimab/cilgavimab in case of lack of seroconversion, effectively in the otherwise high-risk population.
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In this episode, Peter Wehrwein, managing editor of Managed Healthcare Executive, speaks with Dr. Rodrigo Cerda. Dr. Cerda has been recently promoted to the position of senior vice president of health services and chief medical officer of Independence Blue Cross in Philadelphia. He is also a member of Managed Healthcare Executive’s editorial advisory board. Peter and Dr. Cerda discuss his new role at the Independence Blue Cross, what it means to be a chief medical officer at an insurer these days, valued-based care, social determinants of health, and, of course, the pandemic.
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How More Prompt Action Could Have Saved Thousands of U.S. COVID-19 Deaths
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A Cup or Two of Joe a Day Could Keep COVID-19 Infection Away
November 19th 2023Coffee, rich in polyphenolic compounds like chlorogenic acid (CGA), caffeic acid (CAA), cafestol, melanoidins and trigonelline, has been recognized as a dominant source of CGA in various studies. Previous studies suggest that CGA in coffee can positively impact blood pressure, lipid profile, glycemia and insulin resistance.
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The Challenges, Strategies of COVID-19 Misinformation Interventions
November 16th 2023COVID-19 misinformation interventions should involve public health experts, establish consistent outcome measures and more to address health misinformation at individual, community and systems levels, according researchers of a recent study.
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