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As a wave of blockbuster biologics face loss of exclusivity, some hope that there may be a “second phase” of biosimilar adoption.

A new study in JAMA Network Open projects that the number of Medicare beneficiaries 65 and older living with HIV will grow from approximately 122,000 to 194,000 by 2035, driving cumulative Medicare costs of $187.2 billion, with antiretroviral therapy alone accounting for 63% of that spending.

Provider networks are a fundamental part of U.S. health insurance. But an increasing number of self-insured employers are offering low-premium health plans without networks, and the CMS is working toward having such plans available on the ACA marketplaces.

The premiums may be low but the deductibles are high. More people are enrolling in ACA bronze plans because of the expiration of COVID-19 enhanced subsidies. And the Trump administration is taking steps to encourage enrollment in high-deductible, low-premium catastrophic coverage.

Marc Elia of Invyvid explains the difference between vaccines and monoclonal antibodies.

Improving outcomes in chronic conditions will require eliminating friction and creating a connected foundation that supports people continuously.

University of Vermont Health dermatologists argue that is wasteful and causes undue worry to routinely test patients taking isotretinion for elevated liver enzymes and triglycerides.

An American Diabetes Association survey has found that high insulin costs are straining patients financially, with 1 in 3 cutting groceries. A new Senate bill aims to limit copays and boost PBM rebate transparency.

The findings from a matched cohort study add to the body of evidence that people with vitiligo are likely to contend with other health problems.

In this interview, Marc Elia argues that monoclonal antibodies like VYD2311 offer a fundamentally different approach to COVID-19 prevention than vaccines, delivering protective antibodies directly rather than triggering an immune response, which he says could improve tolerability.

GLP-1 receptor agonists can help reduce inflammation and improve blood vessel function in patients with peripheral artery disease.

United Healthcare, Express Scripts, Cigna, Optum Rx and TRICARE offer Neffy without restriction. Neffy is an epinephrine nasal spray available for anaphylaxis.

If approved to treat patients with mantle cell lymphoma, Brukinsa plus rituximab would be the first chemotherapy-free regimen for newly diagnosed patients.

There are lots of clues. But far more research is needed to find out whether metabolic dysfunction-associated steatotic liver disease (MASLD) plays a causative role in breast cancer.

The approval was supported by the pivotal phase 3 THRIVE and THRIVE-2 trials, which evaluated veligrotug in active and chronic TED.

Healthcare leaders rank improving the patient experience ahead of digital transformation and cost reduction, and it can't be done without a trusted identity foundation.

Rather than considering prior authorization metrics separately, a Friction Index combines,

The approach of pairing an ecological framework with AI methods offers a new way to identify where diabetes risk concentrates.

Built from the experiences of patients, advocates and clinicians, a new MASH patient journey map offers a roadmap for navigating diagnosis and highlights the need for greater public understanding of the disease.

Financial sustainability and innovation are interdependent, as clinician-led contracting strategies that improve outcomes generate savings that fund further innovation.

A new meta-analysis suggests that combining immunotherapy and chemotherapy might be the best choice for treating advanced non-small cell lung cancer.

Addressing social determinants of health is now a strategic pillar of organizational planning, compliance, and long-term sustainability.

Results from the DAPHNe trial point to ctDNA as having a role in guiding treatment, but the researchers and a commentator say more research needs to be done before determining exactly what it is.

Age, skin phototype, and personal history of skin cancer are easily captured data elements that could form the basis of a practical, risk-stratified approach to surveillance.

The two conditions can have similar manifestations but differ in prognosis and treatment, which makes an accurate, early diagnosis important.

Survodutide is a dual GLP-1/glucagon receptor agonist that was also able to normalize liver fat in 61% of patients with metabolic dysfunction-associated steatotic liver disease.

Kutscher says MDVIP is expanding into specialty care and eyeing pediatrics.

If prospective studies of clinical outcomes confirm the findings, one near-term application of the research might be using automated analysis of speech samples to monitor patients with schizophrenia.